摘要: Puberty refers to the achievement of reproductive maturity. It is a period acceleration in linear growth, increase muscle mass, and changes ovarian testicular function (1). The initial evaluation young child with early sexual development distinguish true central precocious puberty activation hypothalamic/pituitary/gonadal axis from peripheral or gonadotropin-independent so that specific treatment can be initiated. decision treat medically requires an understanding variable progression puberty. Hence, should identify those children who might benefit by long-acting analogs Gonadotropin Releasing Hormone (GnRHa) halt their pubertal progression.