Presence of Class I and Class II Integrons in Methicilin Resistant Staphylococci and Their Relations with Antibiotic Resistance: A Preliminary Study from Turkey

作者: Defne Gumus , Mine Ang-Kucuker , Fatma Kalayci-Yuksek , Mert Caliskan , Acelya Gumus

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摘要: Background: Emergence of antibiotic resistance is a major public health concern. It known that transferred by different ways. Integrons as one these mechanisims cause to spread in Gram negative bacteria but also it shown be effective for transferring genes positive bacteria. In the present study we aimed examine prevalence class I and II integrons MRSA MRCNS strains isolated from patients determine relationship between presence integrons. Methods: Sixty four 62 were included this study. Antibiotic susceptibility testings performed. Genomic plasmid DNAs extracted Polymerase Chain Reaction (PCR) was used detection intI intII genes. The PCR products visualised 1.5 % agarose gel electrophoresis. Pearson chi-square test Fisher’s exact comparing categorical variables. Results: Among 126 staphylococci 11 (8.7% - 4 7 MRCNS) carry integron; whereas (5.5%) positive. Both detected possess (3.2%). There no statistically significant relation each antibiotics (p>0.05). Conclusion & Recommendation: did not find any rates suggest results showed an important data about extended distributions only among staphylococci. Keywords: MRSA, MRCNS, integron, anbiotic DOI: 10.7176/JHMN/75-07

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