[Long-term effects of the treatment with risperidone versus conventional neuroleptics on the neuropsychological performance of euthymic bipolar patients].

摘要: INTRODUCTION: An increasing number of studies point to the persistence cognitive deficits in a subpopulation euthymic bipolar disorders. Atypical antipsychotics represent an interesting alternative treatment compared with conventional neuroleptics, because former might cause lesser affection functions. The objective this study was establish, for patients who need long-term antipsychotic treatment, neuropsychological and outcome (occupational functioning) differences between treated risperidone neuroleptics. SUBJECTS AND METHOD: A sample twenty RDC I II were assessed by means SADS. All them (HDRS < 8; YMRS 6) at least 6 months antipsychotics. Patients received (N = 11) neuroleptics 9) respect their profile. RESULTS: There significant Trail Making Test-part B (p 0.038) occupational 0.024), favouring risperidone. no other tests, but tended score higher most measures performance. CONCLUSIONS: Among preventing relapses, receive show more flexibility better adaptation than