作者: Victoria Borg Debono , Shiyuan Zhang , Chenglin Ye , James Paul , Aman Arya
关键词:
摘要: Background: Randomized controlled trials (RCTs) are routinely used in systematic reviews and meta-analyses that help inform healthcare policy decision making. The proper reporting of RCTs is important because it acts as a proxy for health care providers researchers to appraise the quality methodology, conduct analysis an RCT. aims this study analyse overall 23 were metaanalysis by assessing 3 key methodological items, determine factors associated with high reporting. It hypothesized studies larger sample sizes, have funding reported, published journals higher impact factor adopted or endorsed CONSORT statement will be better items. Methods: We systematically reviewed within anesthesiology related post-operative pain management meta-analysis. included all used, which parallel design addressed use femoral nerve block improving outcomes after total knee arthroplasty. Data abstraction was done independently two reviewers. main were: 1) 15 point score (OQRS) based on Consolidated Standards Reporting Trials (CONSORT) 2) item (KMIS) allocation concealment, blinding intention-to-treat analysis. Results: Twenty-three included. median OQRS 9.0 (Interquartile Range=3). A multivariable regression did not show any significant association between KMIS our four predictor variables improve direction magnitude results when compared similar suggest size improved Conclusions: anesthesia meta-analysis poor moderate. information gained from should register urgency clear transparent make literature accessible comparable.