Targeting the Mitochondria in Cardiovascular Diseases
作者： José Marín-García
DOI: 10.1007/978-1-4614-4599-9_23
关键词:
摘要: While progress achieved in mitochondrial research has been mainly used the discovery of pathogenesis neuromuscular, cardiovascular, and other diseases, more specific studies are needed to determine severity heart defects (either primary or secondary myocardial alterations) its contribution pathophysiology cardiovascular diseases. This new knowledge could be applied identify mitochondrial-targeted drugs not only failure syndrome but also reverse, at least slow, potential changes cardiac cell structure function which occur many diseases as well aging heart.
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Mina K. Chung, Vitamins, supplements, herbal medicines, and arrhythmias. Cardiology in Review. ,vol. 12, pp. 73- 84 ,(2004) , 10.1097/01.CRD.0000091839.22076.F4
R. A. J. Smith, C. M. Porteous, A. M. Gane, M. P. Murphy, Delivery of bioactive molecules to mitochondria in vivo Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 5407- 5412 ,(2003) , 10.1073/PNAS.0931245100
José Marín-García, Michael J. Goldenthal, Understanding the impact of mitochondrial defects in cardiovascular disease: A review Journal of Cardiac Failure. ,vol. 8, pp. 347- 361 ,(2002) , 10.1054/JCAF.2002.127774
Nils-Göran Larsson, Pierre Rustin, Animal models for respiratory chain disease Trends in Molecular Medicine. ,vol. 7, pp. 578- 581 ,(2001) , 10.1016/S1471-4914(01)02167-0
A. McGregor, R. Temperley, Z.M.A. Chrzanowska-Lightowlers, R. N Lightowlers, Absence of expression from RNA internalised into electroporated mammalian mitochondria. Molecular Genetics and Genomics. ,vol. 265, pp. 721- 729 ,(2001) , 10.1007/S004380100469
Jack P. Jenuth, Alan C. Peterson, Eric A. Shoubridge, Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice Nature Genetics. ,vol. 16, pp. 93- 95 ,(1997) , 10.1038/NG0597-93
Hiroshi Ito, Yoshiaki Taniyama, Katsuomi Iwakura, Nagahiro Nishikawa, Tohru Masuyama, Tsunehiko Kuzuya, Masatsugu Hori, Yorihiko Higashino, Kenshi Fujii, Takazo Minamino, Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction Journal of the American College of Cardiology. ,vol. 33, pp. 654- 660 ,(1999) , 10.1016/S0735-1097(98)00604-4
Paul S Brookes, Stanley B Digerness, Dale A Parks, Victor Darley-Usmar, Mitochondrial function in response to cardiac ischemia-reperfusion after oral treatment with quercetin Free Radical Biology and Medicine. ,vol. 32, pp. 1220- 1228 ,(2002) , 10.1016/S0891-5849(02)00839-0
Steven E Lipshultz, Nader Rifai, Virginia M Dalton, Donna E Levy, Lewis B Silverman, Stuart R Lipsitz, Steven D Colan, Barbara L Asselin, Ronald D Barr, Luis A Clavell, Craig A Hurwitz, Albert Moghrabi, Yvan Samson, Marshall A Schorin, Richard D Gelber, Stephen E Sallan, None, The Effect of Dexrazoxane on Myocardial Injury in Doxorubicin-Treated Children with Acute Lymphoblastic Leukemia The New England Journal of Medicine. ,vol. 351, pp. 145- 153 ,(2004) , 10.1056/NEJMOA035153
Brett H. Graham, Katrina G. Waymire, Barbara Cottrell, Ian A. Trounce, Grant R. MacGregor, Douglas C. Wallace, A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator Nature Genetics. ,vol. 16, pp. 226- 234 ,(1997) , 10.1038/NG0797-226