IBS-GEC ESTRO-ABS Recommendations for CT Based Contouring in Image Guided Adaptive Brachytherapy for Cervical cancer.

摘要: Abstract MR Imaging is regarded as the gold standard for Image Gudied Adaptive Brachytherapy (IGABT) for cervical cancer. However, its wide applicability limited by availability, logistics and financial implications. Use of alternative imaging like CTand Ultrasound (US) IGABT has been attempted. In order to arrive at a systematic, uniform international approach CT based definition contouring target structures, GEC ESTRO, IBS ABS agreed jointly develop such recommendations on the concepts terms as published in ICRU Report 89. The minimum requirements are clinical examination & documentation, or diagnosis minimum, with applicator place. (i) assessment GTV brachytherapy, (ii) categorizing response external radiation into different remission patterns, (iii) defining various clinico-radiological environments (iv) delineation time brachytherapy situ. 4 categories within 8 defined environments, aim improving accuracy using CT, US MRI available. For each environment, there an attempt minimize specific uncertainties best possible accuracy. Evaluating feasibility reproducibility, achieve benchmark towards standard further research including outcomes Based will become next steps. Background Rationale Cervical cancer fourth most common among women globally, estimated 579,200 new cases 316,800 deaths worldwide 2018 (1). incidence higher low-middle income (LMIC) low (LIC) countries settings accounting 85% locally advanced worldwide, which sufficient resources management, especially radiotherapy facilities, represents major challenge. (2)