Attentional flexibility in the thalamus: now we're getting SOMwhere

作者: Christopher D Makinson , John R Huguenard

DOI: 10.1038/NN.3902

关键词:

摘要: Loss of the receptor tyrosine kinase ErbB4 in somatostatin (SOM) inhibitory neurons thalamic reticular nucleus (TRN) enhances top-down cortical feedback, improving feature detection at cost reduced ability to switch attention. The study furthers our understanding circuit mechanisms underlying TRN function.

参考文章(15)
Sandra Ahrens, Santiago Jaramillo, Kai Yu, Sanchari Ghosh, Ga-Ram Hwang, Raehum Paik, Cary Lai, Miao He, Z Josh Huang, Bo Li, ErbB4 regulation of a thalamic reticular nucleus circuit for sensory selection Nature Neuroscience. ,vol. 18, pp. 104- 111 ,(2015) , 10.1038/NN.3897
Scott J. Cruikshank, Hayato Urabe, Arto V. Nurmikko, Barry W. Connors, Pathway-Specific Feedforward Circuits between Thalamus and Neocortex Revealed by Selective Optical Stimulation of Axons Neuron. ,vol. 65, pp. 230- 245 ,(2010) , 10.1016/J.NEURON.2009.12.025
Lin Mei, Wen-Cheng Xiong, Neuregulin 1 in neural development, synaptic plasticity and schizophrenia Nature Reviews Neuroscience. ,vol. 9, pp. 437- 452 ,(2008) , 10.1038/NRN2392
Michael Krause, William E Hoffmann, Mihály Hajós, Auditory sensory gating in hippocampus and reticular thalamic neurons in anesthetized rats. Biological Psychiatry. ,vol. 53, pp. 244- 253 ,(2003) , 10.1016/S0006-3223(02)01463-4
B. Zikopoulos, H. Barbas, Pathways for Emotions and Attention Converge on the Thalamic Reticular Nucleus in Primates The Journal of Neuroscience. ,vol. 32, pp. 5338- 5350 ,(2012) , 10.1523/JNEUROSCI.4793-11.2012
Jeanne T Paz, Astra S Bryant, Kathy Peng, Lief Fenno, Ofer Yizhar, Wayne N Frankel, Karl Deisseroth, John R Huguenard, A new mode of corticothalamic transmission revealed in the Gria4-/- model of absence epilepsy Nature Neuroscience. ,vol. 14, pp. 1167- 1173 ,(2011) , 10.1038/NN.2896
Kerry McAlonan, James Cavanaugh, Robert H. Wurtz, Guarding the gateway to cortex with attention in visual thalamus Nature. ,vol. 456, pp. 391- 394 ,(2008) , 10.1038/NATURE07382
F. Crick, Function of the thalamic reticular complex: the searchlight hypothesis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 81, pp. 4586- 4590 ,(1984) , 10.1073/PNAS.81.14.4586
Michael M. Halassa, Zhe Chen, Ralf D. Wimmer, Philip M. Brunetti, Shengli Zhao, Basilis Zikopoulos, Fan Wang, Emery N. Brown, Matthew A. Wilson, State-Dependent Architecture of Thalamic Reticular Subnetworks Cell. ,vol. 158, pp. 808- 821 ,(2014) , 10.1016/J.CELL.2014.06.025