摘要: What will happen after a complete sequence of the human genome is available? Eric Lander argues that it will be the beginning of a new phase of research. He presents 10 goals for the future that are related to a global view of biology. The author is at the Whitehead Institute for Biomedical Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
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harvard.edu参考文章(6)
M. Schena, D. Shalon, R. W. Davis, P. O. Brown, Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray Science. ,vol. 270, pp. 467- 470 ,(1995) , 10.1126/SCIENCE.270.5235.467
Paul L. Bartel, Jennifer A. Roecklein, Dhruba SenGupta, Stanley Fields, A protein linkage map of Escherichia coli bacteriophage T7. Nature Genetics. ,vol. 12, pp. 72- 77 ,(1996) , 10.1038/NG0196-72
H. McAdams, L Shapiro, Circuit Simulation of Genetic Networks Science. ,vol. 269, pp. 650- 656 ,(1995) , 10.1126/SCIENCE.7624793
L. Holm, C. Sander, Mapping the Protein Universe Science. ,vol. 273, pp. 595- 602 ,(1996) , 10.1126/SCIENCE.273.5275.595
M. Chee, R. Yang, E. Hubbell, A. Berno, X. C. Huang, D. Stern, J. Winkler, D. J. Lockhart, M. S. Morris, S. P. A. Fodor, Accessing Genetic Information with High-Density DNA Arrays Science. ,vol. 274, pp. 610- 614 ,(1996) , 10.1126/SCIENCE.274.5287.610
T. J. Hudson, L. D. Stein, S. S. Gerety, J. Ma, A. B. Castle, J. Silva, D. K. Slonim, R. Baptista, L. Kruglyak, S.-H. Xu, X. Hu, A. M. E. Colbert, C. Rosenberg, M. P. Reeve-Daly, S. Rozen, L. Hui, X. Wu, C. Vestergaard, K. M. Wilson, J. S. Bae, S. Maitra, S. Ganiatsas, C. A. Evans, M. M. DeAngelis, K. A. Ingalls, An STS-Based Map of the Human Genome Science. ,vol. 270, pp. 1945- 1954 ,(1995) , 10.1126/SCIENCE.270.5244.1945