Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration.

作者: Wassim Abida , Akash Patnaik , David Campbell , Jeremy Shapiro , Alan H Bryce

DOI: 10.1200/JCO.20.01035

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摘要: PURPOSEBRCA1 or BRCA2 (BRCA) alterations are common in men with metastatic castration-resistant prostate cancer (mCRPC) and may confer sensitivity to poly(ADP-ribose) polymerase inhibitors. We pres...

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