Cell death and diabetic cardiomyopathy.

作者: Lu Cai , Y. James Kang

DOI: 10.1385/CT:3:3:219

关键词:

摘要: Myocardial cell death is a key element in the pathogenesis and progression of various etiological cardiomyopathies such as ischemia-reperfusion, toxic exposure, and various chronic diseases including myocardial infarction, atherosclerosis, and endothelial dysfunction. Myocardial cell death is also observed in the hearts of diabetic patients and antimal models; however, its importance in the development of diabetic cardiomyopathy is not completely understood. The goal of this review is to summarize our current …

参考文章(84)
Gary D. Lopaschuk, Fatty Acid Metabolism in the Heart Following Diabetes Springer, Boston, MA. pp. 215- 251 ,(1996) , 10.1007/978-1-4613-1269-7_10
P. Anversa, J. Kajstura, G. Olivetti, Wei Cheng, S. Krajewski, K. Reiss, J. C. Reed, E. H. Sonnenblick, W. A. Clark, Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Laboratory Investigation. ,vol. 74, pp. 86- 107 ,(1996)
The heart in diabetes Kluwer Academic Pub.. ,(1996) , 10.1007/978-1-4613-1269-7
Mary Lynn Bajt, Ye-Shih Ho, Steven L. Vonderfecht, Hartmut Jaeschke, Reactive Oxygen as Modulator of TNF and Fas Receptor-Mediated ApoptosisIn Vivo: Studies with Glutathione Peroxidase-Deficient Mice Antioxidants & Redox Signaling. ,vol. 4, pp. 733- 740 ,(2002) , 10.1089/152308602760598873
Takeshi Nishikawa, Diane Edelstein, Xue Liang Du, Sho-ichi Yamagishi, Takeshi Matsumura, Yasufumi Kaneda, Mark A. Yorek, David Beebe, Peter J. Oates, Hans-Peter Hammes, Ida Giardino, Michael Brownlee, Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Nature. ,vol. 404, pp. 787- 790 ,(2000) , 10.1038/35008121
L. DAVID TOMEI, SAMUIL R. UMANSKY, Apoptosis and the Heart Annals of the New York Academy of Sciences. ,vol. 946, pp. 160- 168 ,(2001) , 10.1111/J.1749-6632.2001.TB03910.X
D. J. Paulson, M. F. Crass, Endogenous triacylglycerol metabolism in diabetic heart American Journal of Physiology-heart and Circulatory Physiology. ,vol. 242, ,(1982) , 10.1152/AJPHEART.1982.242.6.H1084
BERNARD SWYNGHEDAUW, Molecular Mechanisms of Myocardial Remodeling Physiological Reviews. ,vol. 79, pp. 215- 262 ,(1999) , 10.1152/PHYSREV.1999.79.1.215
A. D Timmis, Diabetic heart disease: clinical considerations Heart. ,vol. 85, pp. 463- 469 ,(2001) , 10.1136/HEART.85.4.463