作者: Katherine Rojas , Joan Overhauser
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摘要: Few polymorphic markers have been mapped to chromosome 18 compared with other human chromosomes. Recently, a concerted effort has made generate microsatellite genetic linkage map of using that also physically the chromosome. However, distances between some in this are as large 28.5 cM. Thus, additional needed complement and extend map. Twenty-one by Weissenbach et al. Although appear be spaced at regular intervals along based on recombination frequencies, physical locations these not determined. To determine location 21 18, were regionally panel 20 somatic cell hybrids contain deletions or translocations involving 18. The localizations determined genomic DNA from PCR experiments. 9 refs., 1 fig.