Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells.

Christophe Louandre, Zakaria Ezzoukhry, Corinne Godin, Jean-Claude Barbare, Jean-Claude Mazière, Bruno Chauffert, Antoine Galmiche, Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib. International Journal of Cancer. ,vol. 133, pp. 1732- 1742 ,(2013) , 10.1002/IJC.28159

Yunha Kim, Yong-Sook Kim, Dong Eun Kim, Jee Suk Lee, Ji Hoon Song, Ha-Gyeong Kim, Dong-Hyung Cho, Seong-Yun Jeong, Dong-Hoon Jin, Se Jin Jang, Hyang-Sook Seol, Young-Ah Suh, Seung Jin Lee, Choung-Soo Kim, Jae-Young Koh, Jung Jin Hwang, BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. Autophagy. ,vol. 9, pp. 2126- 2139 ,(2013) , 10.4161/AUTO.26308

Joseph D. Mancias, Xiaoxu Wang, Steven P. Gygi, J. Wade Harper, Alec C. Kimmelman, Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy Nature. ,vol. 509, pp. 105- 109 ,(2014) , 10.1038/NATURE13148

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht, Rachid Skouta, Eleina M. Zaitsev, Caroline E. Gleason, Darpan N. Patel, Andras J. Bauer, Alexandra M. Cantley, Wan Seok Yang, Barclay Morrison, Brent R. Stockwell, Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death Cell. ,vol. 149, pp. 1060- 1072 ,(2012) , 10.1016/J.CELL.2012.03.042

Wan Seok Yang, Rohitha SriRamaratnam, Matthew E. Welsch, Kenichi Shimada, Rachid Skouta, Vasanthi S. Viswanathan, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Clary B. Clish, Lewis M. Brown, Albert W. Girotti, Virginia W. Cornish, Stuart L. Schreiber, Brent R. Stockwell, Regulation of Ferroptotic Cancer Cell Death by GPX4 Cell. ,vol. 156, pp. 317- 331 ,(2014) , 10.1016/J.CELL.2013.12.010

Junwei Shi, Christopher R. Vakoc, The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition Molecular Cell. ,vol. 54, pp. 728- 736 ,(2014) , 10.1016/J.MOLCEL.2014.05.016

Kun Wang, Cui-Yun Liu, Lu-Yu Zhou, Jian-Xun Wang, Man Wang, Bing Zhao, Wen-Ke Zhao, Shi-Jun Xu, Li-Hua Fan, Xiao-Jie Zhang, Chang Feng, Chao-Qun Wang, Yan-Fang Zhao, Pei-Feng Li, APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p. Nature Communications. ,vol. 6, pp. 6779- ,(2015) , 10.1038/NCOMMS7779

Xiaofang Sun, Zhanhui Ou, Ruochan Chen, Xiaohua Niu, De Chen, Rui Kang, Daolin Tang, Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells Hepatology. ,vol. 63, pp. 173- 184 ,(2016) , 10.1002/HEP.28251

Philipp Rathert, Mareike Roth, Tobias Neumann, Felix Muerdter, Jae-Seok Roe, Matthias Muhar, Sumit Deswal, Sabine Cerny-Reiterer, Barbara Peter, Julian Jude, Thomas Hoffmann, Łukasz M Boryń, Elin Axelsson, Norbert Schweifer, Ulrike Tontsch-Grunt, Lukas E Dow, Davide Gianni, Mark Pearson, Peter Valent, Alexander Stark, Norbert Kraut, Christopher R Vakoc, Johannes Zuber, None, Transcriptional plasticity promotes primary and acquired resistance to BET inhibition Nature. ,vol. 525, pp. 543- 547 ,(2015) , 10.1038/NATURE14898

Jeff Settleman, Cancer: Bet on drug resistance. Nature. ,vol. 529, pp. 289- 290 ,(2016) , 10.1038/NATURE16863