Chronic Neurologic Manifestations of Lyme Disease

摘要: Abstract Background and Methods. Lyme disease, caused by the tick-borne spirochete Borrelia burgdorferi, is associated with a wide variety of neurologic manifestations. To define further chronic abnormalities we studied 27 patients (age range, 25 to 72 years) previous signs current evidence immunity B. symptoms no other identifiable cause. Eight had been followed prospectively for 8 12 years after onset infection. Results. Of patients, 24 (89 percent) mild encephalopathy that began 1 month 14 disease was characterized memory loss, mood changes, or sleep disturbance. impairment on neuropsychological tests, 18 increased cerebrospinal fluid protein levels, intrathecal production antibody both. Nineteen (70 polyneuropathy wi...