Microgel photonics and lab on fiber technology for advanced label-free fiber optic nanoprobes

摘要: We experimentally demonstrate a novel optical fiber label free optrode platform resulting from the integration between two rapidly emerging technologies such as Lab-on-Fiber Technology (LOFT) and Microgel Photonics (MPs). The device consists of microgel (MG) layer painted on metallic slabs supporting plasmonic resonances, directly integrated the optical tip. A molecular binding event induces significant changes in MG thickness (and consequently in its 'equivalent' refractive index) an evident wavelength shift resonant feature. As case study, glucose-responsive MGs have been synthesized by incorporating into gel matrix boronic acid moieties, whose interaction with glucose rules driving forces for swelling. Our results pave way new technological routes aimed to develop advanced optic nanoprobes.