The Isolation and Characterization of Dihydropteridine Reductase from Sheep Liver
作者： Jonathan E. Craine , E. Stanley Hall , Seymour Kaufman
DOI: 10.1016/S0021-9258(19)44767-4
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摘要: Abstract Dihydropteridine reductase has been obtained from sheep liver in essentially homogeneous form. The enzyme exists as a dimer of molecular weight 41,000 to 42,800. subunit determined be 21,300. In the presence quinonoid tautomer either dihydrobiopterin or dihydro-6, 7-dimethylpterin, DPNH is better substrate than TPNH. Evidence indicates that activity this far greater known pterindependent hydroxylases all tissues examined.
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sci-hub.st 参考文章(43)
V. P. Whittaker, E. G. Gray, The isolation of nerve endings from brain: An electron microscopic study of cell fragments derived by homogenization and centrifugation Journal of Anatomy. ,vol. 96, pp. 79- 88 ,(1962)
Seymour Kaufman, Studies on the Structure of the Primary Oxidation Product Formed from Tetrahydropteridines during Phenylalanine Hydroxylation Journal of Biological Chemistry. ,vol. 239, pp. 332- 338 ,(1964) , 10.1016/S0021-9258(18)51786-5
Sidney Futterman, ENZYMATIC REDUCTION OF FOLIC ACID AND DIHYDROFOLIC ACID TO TETRAHYDROFOLIC ACID Journal of Biological Chemistry. ,vol. 228, pp. 1031- 1038 ,(1957) , 10.1016/S0021-9258(18)70678-9
G.H. Beaven, E.R. Holiday, Ultraviolet absorption spectra of proteins and amino acids. Advances in Protein Chemistry. ,vol. 7, pp. 319- 386 ,(1952) , 10.1016/S0065-3233(08)60022-4
Seymour Kaufman, The nature of the primary oxidation product formed from tetrahydropteridines during phenylalanine hydroxylation. Journal of Biological Chemistry. ,vol. 236, pp. 804- 810 ,(1961) , 10.1016/S0021-9258(18)64312-1
Seymour Kaufman, Daniel B. Fisher, Purification and Some Physical Properties of Phenylalanine Hydroxylase from Rat Liver Journal of Biological Chemistry. ,vol. 245, pp. 4745- 4750 ,(1970) , 10.1016/S0021-9258(18)62856-X
Seymour Kaufman, A Protein That Stimulates Rat Liver Phenylalanine Hydroxylase Journal of Biological Chemistry. ,vol. 245, pp. 4751- 4759 ,(1970) , 10.1016/S0021-9258(18)62857-1
M.J. Osborn, F.M. Huennekens, Enzymatic Reduction of Dihydrofolic Acid Journal of Biological Chemistry. ,vol. 233, pp. 969- 974 ,(1958) , 10.1016/S0021-9258(18)64688-5
Seymour Kaufman, A NEW COFACTOR REQUIRED FOR THE ENZYMATIC CONVERSION OF PHENYLALANINE TO TYROSINE Journal of Biological Chemistry. ,vol. 230, pp. 931- 939 ,(1958) , 10.1016/S0021-9258(18)70516-4
Seymour Kaufman, Studies on the mechanism of the enzymatic conversion of phenylalanine to tyrosine. Journal of Biological Chemistry. ,vol. 234, pp. 2677- 2682 ,(1959) , 10.1016/S0021-9258(18)69758-3