Inclusion Complexes of the Natural Product Gossypol. Crystal Structure of the 2" 1 Complex of Gossypol with Amyl Acrylate

摘要: The crystal structure of the 2: 1 inclusion complex gossypol with amyl acrylate has been determined by X-ray analysis. crystals (C30H30O8)2⁗C8H14O2 are triclinic, space group P\(\bar 1\),a = 14.425(2),b 15.519(1),c 16.409(2) A, α =97.89(1), β 117.80(1), γ =67.01(1)° (reduced cell:a 15.519(2),c 16.017(2)A, 92.19(1), 115.01(l), =67.01(1)°],V 2986.7(5) A3,Z 2,Dx 1.31 g cm−3, μ(CuKα) 7.40 cm−1,T 292 K. solved direct methods and refined to final R value 0.059 for 5155 observed reflections. molecules bonded via several hydrogen bonds form centrosymmetric tetramers. two independent molecules, A B, related within tetramer a local noncrystallographic 2-fold axis. host in cavities which guest placed. ester molecule interacts pair C-...H-O same chirality belonging unit. amyloxy shows very large thermal motion. It adopts non-extended conformation it can be fitted into cavity formed molecules.