作者: David Hamilton , Nasser Fotouhi-Ardakani , Gerald Batist
DOI: 10.1007/978-1-4615-1173-1_4
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摘要: One of the greatest obstacles in effective chemotherapy neoplastic disease is presence tumor chemoresistance. In some instances, a can be intrinsically resistant to or, other cases, develop resistance during course antineoplastic treatment. This acquired thought occur through selection subpopulation cells as exposed chemotherapy. To complicate chemotherapeutic drug selection, it has been found that once demonstrates one class drugs, will often classes share structural or functional homology