Lymphoid Malignancy and Development, Differentiation, and Function of the Lymphoreticular System

作者: Ann E. Gabrielsen , Max D. Cooper , Raymond D. A. Peterson , Robert A. Good

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摘要: Summary There are 2 pathways of normal lymphoid differentiation. The thymus is responsible for initiation and control cellular differentiation directed toward the small lymphocyte immunity. avian bursa Fabricius, perhaps Peyer9s patches man, initiates controls another pathway plasma cell immunoglobulin production. Thymus-dependent bursa-dependent lymphocytic malignancies have been defined in mouse chicken, respectively, featured by abnormal beginning one or other central organ. It proposed that clinical may also be usefully classified as either system immunoglobulin-producing malignancies. In this view Hodgkin9s disease appears to a disease, more focused study its organ seems indicated.

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