Oesophageal squamous cell carcinoma (ESCC): Advances through omics technologies, towards ESCC salivaomics

作者: Juan José González-Plaza , Nataša Hulak , Eduardo García-Fuentes , Lourdes Garrido-Sánchez , Zhaxybay Zhumadilov

DOI: 10.5582/DDT.2015.01042

关键词:

摘要: Oesophageal Squamous Cell Carcinoma (ESCC) is one of the two main subtypes oesophageal cancer, affecting mainly populations in Asia. Though there have been great efforts to develop methods for a better prognosis, still limitation staging this affection. As result, ESCC detected at advances stages, when interventions on patient do not such positive outcome, leading many cases recurrence and very low 5-year survival rate, causing high mortality. A way decrease number deaths use biomarkers that can trace advance disease early surgical or chemotherapeutic methodologies would greater effect evolution subject. The new throughput omics technologies offer an unprecedented chance screen thousands molecules same time, from which set could be developed. One most convenient types samples saliva, accessible body fluid has advantage being non-invasive patient, easy store process. This review will focus current status regarding salivaomics ESCC, evaluated yet, achievements related diseases.

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