Mutagenicity of the Alternaria metabolites altertoxins I, II, and III.

摘要: The Ames Salmonella typhimurium assay was used to demonstrate that an extract of the mold Alternaria alternata mutagenic. mutagenic fractionated, and test determine which fractions were Subsequently, altertoxins I II a new compound referred as altertoxin III isolated by liquid chromatography shown be hydroxyperylenequinone compounds mass spectrometry infrared, ultraviolet, proton magnetic resonance spectroscopy. Altertoxins I, II, S. TA98, TA100, TA1537 with without metabolic activation.