Effect of aging on human skeletal muscle and motor function.

作者: FRANK W. BOOTH , STEVEN H. WEEDEN , BRIAN S. TSENG

DOI: 10.1249/00005768-199405000-00006

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摘要: The percentage of Americans over the age 65 yr is growing and this trend has heightened interest in aging research. In review human studies, comparisons, as a function age, are made among declines VO2max, work endurance, muscle strength, total cross-sectional area, fiber number, spinal motor neuron unit number. Declines VO2max area leg begin early adulthood. However, an accelerated loss decrease number begins at about 50 age. Losses neurons units become apparent 60 these findings were collected on different subjects. By better defining temporal relationships same subjects, more accurate cause effect relationship may be obtained. Although atrophy attenuated by resistance training with aging, little known effects neurons, units, goal research would to enhance ability promote much independence living possible, i.e., increase quality life our expanding elderly population.

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