Statistical Significance and Clinical Relevance

作者: Sachin S. Bhardwaj , Fabian Camacho , Amy Derrow , Alan B. Fleischer , Steven R. Feldman

DOI: 10.1001/ARCHDERM.140.12.1520

关键词:

摘要: When evaluating the validity of a study, reader must consider both clinical and statistical significance findings. A study that claims relevance may lack sufficient to make meaningful statement. Conversely, shows statistically significant difference in 2 treatment options practicality. The concept power trial refers probability detecting between groups when true exists. We will discuss by examining studies too small identify important differences, so large as differences are not clinically significant, difficult-to-design without very patient populations, those with adequate relevant Dermatologists should focus on P values alone decide whether is useful; it essential magnitude study.

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