Promotion and Suppression of Centriole Duplication Are Catalytically Coupled through PLK4 to Ensure Centriole Homeostasis.

作者: Minhee Kim , Brian P. O’Rourke , Rajesh Kumar Soni , Prasad V. Jallepalli , Ronald C. Hendrickson

DOI: 10.1016/J.CELREP.2016.06.069

关键词:

摘要: PLK4 is the major kinase driving centriole duplication. Duplication occurs only once per cell cycle, forming one new (or daughter) centriole that is tightly engaged to the preexisting (or …

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