A noise measure for copy number analysis on targeted panel sequencing data

作者: Johannes Heuckmann , Tobias Zacherle

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摘要: The present invention relates to a method for determining the statistical noise level in calculation of subject's genetic copy number value massively parallel nucleic acid sequencing data derived from sample, as well sample and determine stratifying subject cancer therapy.

参考文章(7)
Anya Tsalenko, Amir Ben-Dor, Bo Curry, Jayati Ghosh, Method and system for analysis of array-based, comparative-hybridization data ,(2006)
Alexander Krasnitz, James B. Hicks, Anders P. Zetterberg, Methods for assessing probabilistic measures of clinical outcome using genomic profiling ,(2006)
Catalin Barbacioru, Darya I. Chudova, Gengxin Chen, Richard P. Rava, Dimitri Skvortsov, Keith W. Jones, Sven Duenwald, David A. Comstock, Using cell-free dna fragment size to determine copy number variations ,(2016)
AmirAli Talasaz, Helmy Eltoukhy, Bahram Ghaffarzadeh Kermani, Nnamdi Ihuegbu, Detection and treatment of disease exhibiting disease cell heterogeneity and systems and methods for communicating test results ,(2015)
Chen Zhao, Tong Liu, Cosmin Deciu, Amin Mazloom, Yijin Wu, Genetic copy number alteration classifications ,(2017)