In Situ Live-Cell Nucleus Fluorescence Labeling with Bioinspired Fluorescent Probes
作者： Pan Ding , Houyu Wang , Bin Song , Xiaoyuan Ji , Yuanyuan Su
DOI: 10.1021/ACS.ANALCHEM.6B04427
关键词:
摘要: Fluorescent imaging techniques for visualization of nuclear structure and function in live cells are fundamentally important exploring major cellular events. The ideal labeling method is capable realizing label-free, situ, real-time, long-term nucleus cells, which can fully obtain the nucleus-relative information effectively alleviate negative effects alien probes on metabolism. However, current established fluorescent probes-based strategies (e.g., proteins-, organic dyes-, organic/inorganic nanoparticles-based techniques) unable to simultaneously realize long-term, real-time labeling, resulting inevitable difficulties visualizing cells. To this end, we present a type bioinspired probes, highly efficacious situ label-free tracking manners. Typically, bioi...
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