Investigations into the cancer stem cell niche using in-vitro 3-D tumor models and microfluidics.

Louis Vermeulen, Felipe De Sousa E Melo, Maartje van der Heijden, Kate Cameron, Joan H. de Jong, Tijana Borovski, Jurriaan B. Tuynman, Matilde Todaro, Christian Merz, Hans Rodermond, Martin R. Sprick, Kristel Kemper, Dick J. Richel, Giorgio Stassi, Jan Paul Medema, Wnt activity defines colon cancer stem cells and is regulated by the microenvironment Nature Cell Biology. ,vol. 12, pp. 468- 476 ,(2010) , 10.1038/NCB2048

Isabel M. Pires, Zuzana Bencokova, Manuela Milani, Lisa K. Folkes, Ji-Liang Li, Mike R. Stratford, Adrian L. Harris, Ester M. Hammond, Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability Cancer Research. ,vol. 70, pp. 925- 935 ,(2010) , 10.1158/0008-5472.CAN-09-2715

Xin Lu, Yibin Kang, Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis Clinical Cancer Research. ,vol. 16, pp. 5928- 5935 ,(2010) , 10.1158/1078-0432.CCR-10-1360

Ece Yildiz-Ozturk, Ozlem Yesil-Celiktas, Diffusion phenomena of cells and biomolecules in microfluidic devices Biomicrofluidics. ,vol. 9, pp. 052606- 052606 ,(2015) , 10.1063/1.4923263

Christopher Calabrese, Helen Poppleton, Mehmet Kocak, Twala L. Hogg, Christine Fuller, Blair Hamner, Eun Young Oh, M. Waleed Gaber, David Finklestein, Meredith Allen, Adrian Frank, Ildar T. Bayazitov, Stanislav S. Zakharenko, Amar Gajjar, Andrew Davidoff, Richard J. Gilbertson, A Perivascular Niche for Brain Tumor Stem Cells Cancer Cell. ,vol. 11, pp. 69- 82 ,(2007) , 10.1016/J.CCR.2006.11.020

Raghu Kalluri, Robert A. Weinberg, The basics of epithelial-mesenchymal transition Journal of Clinical Investigation. ,vol. 119, pp. 1420- 1428 ,(2009) , 10.1172/JCI39104

Cyrus M. Ghajar, Héctor Peinado, Hidetoshi Mori, Irina R. Matei, Kimberley J. Evason, Hélène Brazier, Dena Almeida, Antonius Koller, Katherine A. Hajjar, Didier Y. R. Stainier, Emily I. Chen, David Lyden, Mina J. Bissell, The perivascular niche regulates breast tumour dormancy Nature Cell Biology. ,vol. 15, pp. 807- 817 ,(2013) , 10.1038/NCB2767

James R. Heath, Mark E. Davis, Nanotechnology and cancer. Annual Review of Medicine. ,vol. 59, pp. 251- 265 ,(2008) , 10.1146/ANNUREV.MED.59.061506.185523

Joseph P. Eder, Jeffrey G. Supko, Jeffrey W. Clark, Thomas A. Puchalski, Rocio Garcia-Carbonero, David P. Ryan, Lawrence N. Shulman, Joann Proper, Moira Kirvan, Barbara Rattner, Susan Connors, Mary T. Keogan, Milos J. Janicek, William E. Fogler, Lowell Schnipper, Nancy Kinchla, Carolyn Sidor, Eric Phillips, Judah Folkman, Donald W. Kufe, Phase I Clinical Trial of Recombinant Human Endostatin Administered as a Short Intravenous Infusion Repeated Daily Journal of Clinical Oncology. ,vol. 20, pp. 3772- 3784 ,(2002) , 10.1200/JCO.2002.02.082

Antonio Sica, Tiziana Schioppa, Alberto Mantovani, Paola Allavena, Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy European Journal of Cancer. ,vol. 42, pp. 717- 727 ,(2006) , 10.1016/J.EJCA.2006.01.003