Composite nano-drug constructed by nanoparticles coupled with pharmaceutical ingredients as well as preparation method and application of composite nano-drug

摘要: The invention discloses a composite nano-drug constructed by nanoparticles coupled with pharmaceutical ingredients as well preparation method and an application of the nano-drug, belongs to technical field drugs. for preparing comprises following operations: modifying amino on surfaces which contain hydroxy in surfaces, activating biological or small-molecular drugs containing hydroxy; then conducting conjugate coupling reaction drugs, so that plurality chemicalbonds are constructed, combining chemical bonds prepare nano-drug. Based upon researches, it is indicated anti-cancer effect can be greatly improved basisof synergistic between active natural (such taxol, ginsenoside other traditional Chinese medicines) nano-material, meanwhile, key breakthrough points also provided researching producing efficient nano-drugs low free from toxic side effects have targeting autonomous performances.