Left ventricular mechanical support with Impella provides more ventricular unloading in heart failure than extracorporeal membrane oxygenation.

摘要: The Impella microaxial-flow pump can directly unload leftventricle (LV) in cases of acute heart failure. Extracorporealmembrane oxygenation (ECMO) is widely used for circula-tory support. Although the clinical effectiveness ECMO hasbeen demonstrated, insufficient LV loading reduction maynot be advantageous myocardial recovery. objectivewas to compare ventricular and reversibil-ity fibrillation (VF) with either orECMO. Six dogs were used. Extracorporeal membrane oxy-genation was established by femoral artery rightatrium. LD inserted ascendingaorta. An failing created sequential coro-nary ligations. Pressure–volume (PV) relationshipswere acquired without a device or Impella.When VF occurred, direct cardioversion performed whilesupported Impella. PV area, which ameasure unloading correlated myo-cardial oxygen consumption, decreased more Impellathan ECMO. Successful defibrillation achieved moreeffectively while under Superior ventricularunloading may provide higher recov-ery potential damaged hearts than have asignificant impact not only on intensive care patients withheart failure but also resuscitation.