Practical recommendations for managing hemolyzed samples in clinical chemistry testing.

摘要: We suggest here a pragmatic approach for managing results of clinical chemistry testing in hemolyzed samples collected from adults/older children, attempting to balance the need produce quality laboratory data with urgency releasing test results. Automatic measurement hemolysis index (H-index) serum or plasma is highly advisable, whilst low-quality assessment this remains less good than visual inspection. Regarding its practical use, when H-index value does not generate an analytically significant bias, can be released, associated analyte variation range between and clinically bias (i.e. exceed reference change [RCV]), hemolysis-sensitive tests released association comment describing direction which are potentially altered, suggesting collect another sample. When exceeding exceeds RCV), should suppressed replaced that biased cannot because sample preanalytically compromised advising recollection If values reach even higher critical cut-off corresponding cell-free hemoglobin concentration ≥10 g/L), all may unreliable hence grossly hemolyzed, also Due inaccuracy imprecision, use corrective formulas adjusting discouraged.