Semliki Forest virus: a probe for membrane traffic in the animal cell.
作者： Kai Simons , Graham Warren
DOI: 10.1016/S0065-3233(08)60296-X
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摘要: Publisher Summary The traffic among the cellular compartments is thought to be mediated by membrane vesicles, which bud from one compartment and fuse with next. Despite continuous exchange of components them, organelles maintain their characteristic protein lipid compositions such that remains selective, thus, avoiding intermixing components. This recycles cell surface interior back again. between ER involves a major sorting problem. Little known how animal has solved this problem in molecular terms. One experimental tool direction provided some enveloped viruses, mature at infected cells. Such viruses include influenza virus, Semliki Forest virus (SFV), Sindbis vesicular stomatitis (VSV). They are extremely simple makeup hence very well characterized. purpose article illustrate use as tools study cell. done context life cycle host will concerned mainly been worked upon chapter. SFV belongs alphaviruses, genus togavirus family.
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