The Immune System, Cytokines, and Biomarkers in Autism Spectrum Disorder.

作者: Anne Masi , Nicholas Glozier , Russell Dale , Adam J. Guastella

DOI: 10.1007/S12264-017-0103-8

关键词:

摘要: Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental condition characterized by variable impairments in communication and social interaction as well restricted interests repetitive behaviors. Heterogeneity of presentation hallmark. Investigations immune system problems ASD, including aberrations cytokine profiles signaling, have been increasing recent times are the subject ongoing interest. With aim establishing whether cytokines utility potential biomarkers that may define subgroup or function an objective measure response to treatment, this review summarizes role system, discusses relationship between brain, behavior, presents previously-identified abnormalities specifically addressing these aberrations. The roles identification also addressed, particularly with respect ASD.

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