Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

作者: Michael C. Milone , Jonathan D. Fish , Carmine Carpenito , Richard G. Carroll , Gwendolyn K. Binder

DOI: 10.1038/MT.2009.83

关键词:

摘要: … contributions of TCR-ζ, CD137 and CD28 signaling domains in mice … that CARs containing CD137 have superior antileukemic … Furthermore, we also find that CARs expressing CD137 …

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