Transition metal complexes of N-heterocyclic carbenes, method of preparation and use in transition metal catalyzed organic transformations

作者: Michael G. Organ , Christopher J. O'Brien , Assam (Eric) B. Kantchev

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摘要: The present invention relates to catalysts of transition metal complexes N-heterocyclic carbenes, their methods preparation and use in chemical synthesis. synthesis, ease-of-use, activity the compounds are substantial improvements over situ catalyst generation. Further, carbenes may be used as precatalysts metal-catalyzed cross-coupling reactions.

参考文章(35)
Alexander Zapf, Anja Frisch, Bernd Kayser, Ralf Karch, Oliver Briel, Kumaravel Selvakumar, Matthias Beller, Novel nickel-carbene, palladium-carbene and platinum-carbene complexes, their production and use in catalytic reactions ,(2003)
Steven P. Nolan, Chunming Zhang, Mark L. Trudell, Jinkun Huang, Catalyst system comprising transition metal and imidazoline-2-ylidene or imidazolidine-2-ylidene ,(2000)
Mihai S. Viciu, Roy A. Kelly, Edwin D. Stevens, Frédéric Naud, Martin Studer, Steven P. Nolan, Synthesis, Characterization, and Catalytic Activity of N-Heterocyclic Carbene (NHC) Palladacycle Complexes Organic Letters. ,vol. 5, pp. 1479- 1482 ,(2003) , 10.1021/OL034264C
Wolfgang A. Herrmann, Claus-Peter Reisinger, Michael Spiegler, Chelating N-heterocyclic carbene ligands in palladium-catalyzed heck-type reactions Journal of Organometallic Chemistry. ,vol. 557, pp. 93- 96 ,(1998) , 10.1016/S0022-328X(97)00736-5
Guido D. Frey, Jan Schütz, Eberhardt Herdtweck, Wolfgang A. Herrmann, Synthesis and Characterization of N-Heterocyclic Carbene Phospha-Palladacycles and Their Properties in Heck Catalysis† Organometallics. ,vol. 24, pp. 4416- 4426 ,(2005) , 10.1021/OM049001G
Mihai S. Viciu, Oscar Navarro, Romain F. Germaneau, Roy A. Kelly, William Sommer, Nicolas Marion, Edwin D. Stevens, Luigi Cavallo, Steven P. Nolan, Synthetic and Structural Studies of (NHC)Pd(allyl)Cl Complexes (NHC = N-heterocyclic carbene) Organometallics. ,vol. 23, pp. 1629- 1635 ,(2004) , 10.1021/OM034319E
Niloufar Hadei, Eric Assen B. Kantchev, Christopher J. O'Brie, Michael G. Organ, Electronic Nature of N-Heterocyclic Carbene Ligands: Effect on the Suzuki Reaction Organic Letters. ,vol. 7, pp. 1991- 1994 ,(2005) , 10.1021/OL050471W
Hélène Lebel, Marc K. Janes, André B. Charette, Steven P. Nolan, Structure and Reactivity of “Unusual” N-Heterocyclic Carbene (NHC) Palladium Complexes Synthesized from Imidazolium Salts Journal of the American Chemical Society. ,vol. 126, pp. 5046- 5047 ,(2004) , 10.1021/JA049759R