DDT and its metabolites in breast milk from the Madeira River basin in the Amazon, Brazil.
作者： Antonio Azeredo , João P.M. Torres , Márlon de Freitas Fonseca , José Lailson Britto , Wanderley Rodrigues Bastos
DOI: 10.1016/J.CHEMOSPHERE.2007.04.090
关键词:
摘要: Abstract Until the 1990s 1,1,1-trichloro-bis-2,2′-(4chlorophenyl) ethane (DDT) was sprayed in walls of house along Madeira River basin, Brazilian Amazon, a region well known for its large number malaria cases. In 1910, Oswaldo Cruz described presence 100% population living some localities from basin. Data available literature point to DDT contamination fishes captured region. Fish is major source dietary protein these people. tends accumulate lipid rich tissues and being eliminated by different events, including lactation. Considering importance feeding breast milk children, associated risks exposure via intake children must be assessed. This main objective this work: analyse p,p′-DDT metabolites p,p′-DDE p,p′-DDD 69 human samples estimate metabolite terms total (total DDT = p,p′-DDE + p,p′-DDD + p,p′-DDT). All showed with ranging 25.4 9361.9 ng DDT/g (median = 369.6 ng lipid) 8.7% estimated daily (EDI), DDT, which higher than acceptable proposed WHO.
core.ac.uk
harvard.edu
fiocruz.br
elsevier.com参考文章(51)
Susan A Korrick, Changzhong Chen, Andrew I Damokosh, Jiatong Ni, Xue Liu, Sung-Il Cho, Larisa Altshul, Louise Ryan, Xiping Xu, Association of DDT with spontaneous abortion: a case-control study. Annals of Epidemiology. ,vol. 11, pp. 491- 496 ,(2001) , 10.1016/S1047-2797(01)00239-3
MARIA AUXILIADORA GARCIA DE OLIVEIRA, ELIANA FREIRES GASPAR DE CARVALHO DORES, Níveis de praguicidas organoclorados no leite materno de uma população de Cuiabá - Mato Grosso Pesticidas: Revista de Ecotoxicologia e Meio Ambiente. ,vol. 8, pp. 77- 90 ,(1998) , 10.5380/PES.V8I0.39517
C. Lutter, V. Iyengar, R. Barnes, T. Chuvakova, G. Kazbekova, T. Sharmanov, Breast milk contamination in Kazakhstan: Implications for infant feeding Chemosphere. ,vol. 37, pp. 1761- 1772 ,(1998) , 10.1016/S0045-6535(98)00241-0
D.C. Johnson, H. Kogo, M. Sen, S.K. Dey, Multiple estrogen action of O,P′-DDP: Initiation and maintenance of pregnancy in the rat Toxicology. ,vol. 53, pp. 79- 87 ,(1988) , 10.1016/0300-483X(88)90238-7
Koidu Norén, Daiva Meironyté, Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20–30 years Chemosphere. ,vol. 40, pp. 1111- 1123 ,(2000) , 10.1016/S0045-6535(99)00360-4
Francisco J.R. Paumgartten, Cristina M. Cruz, Ibrahim Chahoud, Richard Palavinskas, Wolfgang Mathar, PCDDs, PCDFs, PCBs, and other organochlorine compounds in human milk from Rio de Janeiro, Brazil. Environmental Research. ,vol. 83, pp. 293- 297 ,(2000) , 10.1006/ENRS.2000.4062
G Schade, B Heinzow, Organochlorine pesticides and polychlorinated biphenyls in human milk of mothers living in northern Germany: current extent of contamination, time trend from 1986 to 1997 and factors that influence the levels of contamination. Science of The Total Environment. ,vol. 215, pp. 31- 39 ,(1998) , 10.1016/S0048-9697(98)00008-4
Conway Ivan Stacey, William Stanley Perriman, Susan Whitney, Organochlorine pesticide residue levels in human milk: Western Australia, 1979-1980. Archives of Environmental Health. ,vol. 40, pp. 102- 108 ,(1985) , 10.1080/00039896.1985.10545898
Koenraad Marien, Denise M. Laflamme, Determination of a tolerable daily intake of DDT for consumers of DDT contaminated fish from the lower Yakima River, Washington. Risk Analysis. ,vol. 15, pp. 709- 717 ,(1995) , 10.1111/J.1539-6924.1995.TB01343.X
Marli T Oliveira Vannuchi, Lucio Alberto Forti Antunes, Maria Helena Pimenta Pinotti, Resíduos de pesticidas organoclorados em leite materno no município de Londrina, PR Semina-ciencias Agrarias. ,vol. 13, pp. 52- 57 ,(1992) , 10.5433/1679-0367.1992V13N2P52