Dynamic contrast-enhanced ultrasonography (DCE-US) and anti-angiogenic treatments.

摘要: Dynamic contrast-enhanced ultrasonography (DCE-US) is a current functional imaging technique enabling quantitative assessment of tumor perfusion using raw linear data. DCE-US allows calculating several parameters as slope wash-in or area under the curve representing, respectively, blood flow volume. Decrease vascularization can easily be detected in responders after 1 2 weeks anti-angiogenic treatment for gastrointestinal stromal tumors (GIST), renal cell carcinoma (RCC), and hepatocellular (HCC) correlated with progression-free survival overall RCC HCC. supported by French National Cancer Institute (INCa), which currently studying metastatic breast cancer, melanoma, colon carcinoma, well primary to establish optimal timing anticancer efficacy assessments. Currently 479 patients are included 19 centers preliminary results on 400 1096 demonstrated that (AUC) quantified at month could robust parameter predict response 6 months.