Invitro antimicrobial susceptibility pattern of bacterial isolates from wound infections in university of Ilorin Teaching Hospital

摘要: The outcome of 532 wound swabs received from patients with infections in different units the University Ilorin Teaching Hospital Ilorin, Nigeria, over a one year period (July 2000 – June 2001), and routinely procesed by Gram staining culture Microbiology Laboratory, is reported. 444(83.5) all samples cultured positive for bacterial pathogens while 88 (16.5%) were bacteriologically sterile. 272 yielded single isolate 172 mixture two or more organisms. Staphylococcus aureus predominates (35.8%), followed Pseudomonas spp (21.8%), Escherichia coli (15.3%), Klebsiella (13.4%), Proteus (5.6%), Coagulase Negative Staphylococci (3.1%), Streptococcus faecalis (2.8%), Streptococcs pyogenes (0.9%), Group B _-haemolytic Streptococci Acinetobacter (0.3%). Both Gram-positive Gram-negative organisms demonstrated moderate to high vitro sensitivity Ofloxacin Ciprofloxacin (sensitivity rate 70-94%). In Cloxacillin, Erythromycin, Azithromycin Ceftazidime ranged beween 55 90% Gentamicin, Ceftrazidime equally inhibitory effect on negative including spp. 55-90%). The Fluoroquino lones are favoured antimicrobial agents nowadays, as this study. our environment however, combination Cloxacillin Gentamicin an effective empiric alternative when cost considered can be used. need continuous monitoring clinical isolates infection drug resistance, which paramount importance selection antibiotics, emphasized. (Af. J. Clinical Experimental Microbiology: 2002 3(1): 6-10)