Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

作者: Rita Z. Goldstein , Nora D. Volkow

DOI: 10.1038/NRN3119

关键词:

摘要: … Another important cognitive function of the PFC is self-control, and here we focus on the role of the PFC in this process in addiction (Supplementary information S6 (table)). Self control …

参考文章(220)
Wei Qin, Lin Lu, Kai Yuan, Jie Tian, Ya-rong Wang, Qiang Li, You-min Guo, Lan-ying Yang, Wei Wang, Changes in functional connectivity of ventral anterior cingulate cortex in heroin abusers. Chinese Medical Journal. ,vol. 123, pp. 1582- 1588 ,(2010)
Griffith Edwards, Drugs and drug dependence Saxon House , Lexington Books. ,(1976)
Nora D. Volkow, Gene-Jack Wang, Yemin Ma, Joanna S. Fowler, Wei Zhu, Laurence Maynard, Frank Telang, Paul Vaska, Yu-Shin Ding, Christopher Wong, James M. Swanson, Expectation Enhances the Regional Brain Metabolic and the Reinforcing Effects of Stimulants in Cocaine Abusers The Journal of Neuroscience. ,vol. 23, pp. 11461- 11468 ,(2003) , 10.1523/JNEUROSCI.23-36-11461.2003
J. O'Doherty, M. L. Kringelbach, E. T. Rolls, J. Hornak, C. Andrews, Abstract reward and punishment representations in the human orbitofrontal cortex. Nature Neuroscience. ,vol. 4, pp. 95- 102 ,(2001) , 10.1038/82959
Samuel Asensio, Maria J. Romero, Carmina Palau, Amparo Sanchez, Isabel Senabre, Julia L. Morales, Raquel Carcelen, Francisco J. Romero, Altered neural response of the appetitive emotional system in cocaine addiction: an fMRI Study. Addiction Biology. ,vol. 15, pp. 504- 516 ,(2010) , 10.1111/J.1369-1600.2010.00230.X
Léon Tremblay, Wolfram Schultz, Relative reward preference in primate orbitofrontal cortex Nature. ,vol. 398, pp. 704- 708 ,(1999) , 10.1038/19525
Nora D. Volkow, Ting-Kai Li, Drug addiction: the neurobiology of behaviour gone awry Nature Reviews Neuroscience. ,vol. 5, pp. 963- 970 ,(2004) , 10.1038/NRN1539
Joyce H Lowinson, None, Substance Abuse: A Comprehensive Textbook ,(1992)
John A. Matochik, Alan Zametkin, Mary Jeanne Kreek, Lisa Borg, James Schluger, Richard E. Carson, Ann Ho, Kenner C. Rice, Peter Herscovitch, William C. Eckelman, Mitchel A. Kling, Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts. Journal of Pharmacology and Experimental Therapeutics. ,vol. 295, pp. 1070- 1076 ,(2000)