18F-FDG PET/CT as a central tool in the shift from chronic Q fever to Coxiella burnetii persistent focalized infection: A consecutive case series.

摘要: Because Q fever is mostly diagnosed serologically, localizing a persistent focus of Coxiella burnetii infection can be challenging. F-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) could an interesting tool in this context.We performed retrospective study on patients with C infection, who had undergone F-18-FDG PET/CT between 2009 and 2015. When positive results were obtained, we tried to determine if it changed the previous diagnosis by discovering or confirming suspected infection.One hundred sixty-seven benefited from PET/CT. The most frequent clinical subgroup before was no identified despite high IgG1 serological titers (34%). For 59% (n=99) patients, hypermetabolic identified. 62 (62.6%), allowed changed. 24 them, (38.7%), previously unsuspected discovered. Forty-two (42%) more than 1 focus. We observed 21 valvular foci, 34 vascular proportion osteoarticular localizations (n=21). also lymphadenitis (n=27), bone marrow hypermetabolism (n=11), 9 pulmonary localizations.We confirmed that(18)F-FDG central focalized infection. proposed new diagnostic scores for 2 main entities using PET/CT: infections lymphadenitis.