Twin screw granulation: steps in granule growth.
作者： Ranjit M. Dhenge , James J. Cartwright , Michael J. Hounslow , Agba D. Salman
DOI: 10.1016/J.IJPHARM.2012.08.049
关键词:
摘要: The present work focuses on the study of progression granules in different compartments along length screws a twin screw granulator (TSG). effects varying powder feed rate; liquid to solid ratio and viscosity granulation properties was studied. bigger produced at start process were found change terms size, shape strength all conditions investigated. became more spherical their increased length. Tracer also introduced order understand role kneading conveying elements TSG. promoted consolidation breakage while led coalescence, some consolidation. results presented here help provide qualitative quantitative understanding process.
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