New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

作者: Tomáš Etrych , Markéta Jelı́nková , Blanka Řı́hová , Karel Ulbrich

DOI: 10.1016/S0168-3659(01)00281-4

关键词:

摘要: … In both types, the linkage susceptible to hydrolytic cleavage was formed by the reaction of the carbonyl group of Dox with the hydrazide group terminating the oligopeptide side chains of …

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