Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
作者： Kees Brinkman , Jan A Smeitink , Johannes A Romijn , Peter Reiss
DOI: 10.1016/S0140-6736(99)06102-4
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摘要: … Here, we postulate that the mitochondrial toxicity of the nucleoside-analogue reverse-transcriptase inhibitors plays an essential part in the development of this lipodystrophy, similar to …
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