Method of preparing carrier to separate nucleic acids, carrier and micro channel to separate nucleic acids, and method and apparatus for separating nucleic acids

作者: Noriyuki Kishii , Michihiro Ohnishi , Hidetoshi Watanabe , Naoyuki Sasaki , Takuya Kishimoto

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摘要: The present disclosure relates to a method and apparatus for separating nucleic acids. A carrier may include porous microbead having cation-exchangeable groups attached the surface of microbead. Capturing chains modified with positively charged functional base sequence complementary target acid chain are immobilized on In various embodiments, capturing through an ion exchange bond or covalent some cases, has number pores adapted permit solution pass rapidly diffusive solute diffuse into pores. corresponding be passed channel that is packed microbeads so as result in hybridization chain. structured such pressure upon passing does not build significantly.

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