Biophysical Properties of Human Nav1.7 Splice Variants and Their Regulation by Protein Kinase A
作者： Aurélien Chatelier , Leif Dahllund , Anders Eriksson , Johannes Krupp , Mohamed Chahine
关键词:
摘要: The sodium channel Nav1.7 is preferentially expressed in nociceptive neurons and believed to play a crucial role pain sensation. Four alternative splice variants are human dorsal...
sci-hub.se 参考文章(42)
B J Murphy, S Rossie, K S De Jongh, W A Catterall, Identification of the sites of selective phosphorylation and dephosphorylation of the rat brain Na+ channel alpha subunit by cAMP-dependent protein kinase and phosphoprotein phosphatases. Journal of Biological Chemistry. ,vol. 268, pp. 27355- 27362 ,(1993) , 10.1016/S0021-9258(19)74257-4
T.A. Gustafson, E.C. Clevinger, T.J. O'Neill, P.J. Yarowsky, B.K. Krueger, Mutually exclusive exon splicing of type III brain sodium channel alpha subunit RNA generates developmentally regulated isoforms in rat brain. Journal of Biological Chemistry. ,vol. 268, pp. 18648- 18653 ,(1993) , 10.1016/S0021-9258(17)46679-8
KL Schaller, DM Krzemien, NM McKenna, JH Caldwell, Alternatively spliced sodium channel transcripts in brain and muscle. The Journal of Neuroscience. ,vol. 12, pp. 1370- 1381 ,(1992) , 10.1523/JNEUROSCI.12-04-01370.1992
Angela R. Cantrell, Victoria C. Tibbs, Frank H. Yu, Brian J. Murphy, Elizabeth M. Sharp, Yusheng Qu, William A. Catterall, Todd Scheuer, Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. Molecular and Cellular Neuroscience. ,vol. 21, pp. 63- 80 ,(2002) , 10.1006/MCNE.2002.1162
Renu Sarao, Sanjoy K. Gupta, Vanessa J. Auld, Robert J. Dunn, Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs. Nucleic Acids Research. ,vol. 19, pp. 5673- 5679 ,(1991) , 10.1093/NAR/19.20.5673
Angelika Lampert, Sulayman D. Dib-Hajj, Lynda Tyrrell, Stephen G. Waxman, Size Matters: Erythromelalgia Mutation S241T in Nav1.7 Alters Channel Gating Journal of Biological Chemistry. ,vol. 281, pp. 36029- 36035 ,(2006) , 10.1074/JBC.M607637200
Nicholas W. Plummer, James Galt, Julie M. Jones, Daniel L. Burgess, Leslie K. Sprunger, David C. Kohrman, Miriam H. Meisler, Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A Genomics. ,vol. 54, pp. 287- 296 ,(1998) , 10.1006/GENO.1998.5550
T. P. Harty, S. D. Dib-Hajj, L. Tyrrell, R. Blackman, F. M. Hisama, J. B. Rose, S. G. Waxman, Nav1.7 mutant A863P in erythromelalgia : Effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons The Journal of Neuroscience. ,vol. 26, pp. 12566- 12575 ,(2006) , 10.1523/JNEUROSCI.3424-06.2006
Niall C. H. Kerr, Fiona E. Holmes, David Wynick, Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat. Journal of Biological Chemistry. ,vol. 279, pp. 24826- 24833 ,(2004) , 10.1074/JBC.M401281200
Youngsuk Oh, Stephen G. Waxman, Novel splice variants of the voltage-sensitive sodium channel alpha subunit. Neuroreport. ,vol. 9, pp. 1267- 1272 ,(1998) , 10.1097/00001756-199805110-00002