摘要: … stimulate IL-12 production (Fig. … IL- 12 was depleted with antiserum to IL-12. Thus, certain pathogens may preferentially induce cell-mediated immunity because they can stimulate IL-12 …
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R L Coffman, R Chatelain, K Varkila, IL-4 induces a Th2 response in Leishmania major-infected mice. Journal of Immunology. ,vol. 148, pp. 1182- 1187 ,(1992)
P Scott, IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. Journal of Immunology. ,vol. 147, pp. 3149- 3155 ,(1991)
G Huston, S L Swain, A D Weinberg, M English, IL-4 directs the development of Th2-like helper effectors. Journal of Immunology. ,vol. 145, pp. 3796- 3806 ,(1990)
G Le Gros, S Z Ben-Sasson, R Seder, F D Finkelman, W E Paul, Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. Journal of Experimental Medicine. ,vol. 172, pp. 921- 929 ,(1990) , 10.1084/JEM.172.3.921
Robert L Coffman, Timothy R Mosmann, Martin A Giedlin, Holly Cherwinski, Martha W Bond, Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of Immunology. ,vol. 136, pp. 2348- 2357 ,(1986)
C. S. Hsieh, A. B. Heimberger, J. S. Gold, A. O'Garra, K. M. Murphy, Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 6065- 6069 ,(1992) , 10.1073/PNAS.89.13.6065
S H Chan, B Perussia, J W Gupta, M Kobayashi, M Pospísil, H A Young, S F Wolf, D Young, S C Clark, G Trinchieri, Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. Journal of Experimental Medicine. ,vol. 173, pp. 869- 879 ,(1991) , 10.1084/JEM.173.4.869
P Scott, P Natovitz, R L Coffman, E Pearce, A Sher, Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. Journal of Experimental Medicine. ,vol. 168, pp. 1675- 1684 ,(1988) , 10.1084/JEM.168.5.1675
Phillip Scott, Stefan H.E. Kaufmann, The role of T-cell subsets and cytokines in the regulation of infection Immunology Today. ,vol. 12, pp. 346- 348 ,(1991) , 10.1016/0167-5699(91)90063-Y
A. S. Stern, F. J. Podlaski, J. D. Hulmes, Y. C. Pan, P. M. Quinn, A. G. Wolitzky, P. C. Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 6808- 6812 ,(1990) , 10.1073/PNAS.87.17.6808