EEG data collection in children with ASD: The role of state in data quality and spectral power

摘要: Abstract Background Electroencephalography can elucidate neurobiological mechanisms underlying heterogeneity in ASD. Studying the full range of children with ASD introduces methodological challenges stemming from participants’ difficulties tolerating data collection process, leading to diminished EEG retention and increased variability participant ‘state’ during recording. Quantifying state will improve methods aide interpreting results. Objectives Observationally quantify recording; examine its relationship child characteristics, spectral power. Methods Participants included 5–11 year-old (N = 39) age-matched TD (N = 16). were acclimated environment using behavioral strategies. was recorded while participants watched a video bubbles. Participant rated Likert scale (Perceived State Rating: PSR). Results had more elevated PSR than participants. Less retained higher scores, but this not related age or IQ. alpha power compared group. Within group, high decreased frontal Conclusions Given supportive strategies, collected across cognitive levels. influenced both Alpha suppression is linked attention vigilance, suggesting that these less ‘at rest’. This highlights importance considering when conducting studies challenging participants, increase rates influence on variables.