Strain Measurement Using Deformable Image Registration

摘要: The accurate determination of strain in deforming biological tissues is a necessary and important part experimental investigations biomechanics. We have developed method, referred to as Hyperelastic Warping, combine medical image data with solid mechanics analysis approach allow estimation tissue strains the absence detailed information about boundary conditions some cases constitutive information. method makes use provide thus stress fields. mathematical problem search through all admissible configurations for one that minimizes difference between transformed template target collected experimentally. resulting deformation map used determine field. This technique has been applied successfully several soft tissues. paper describes theory, implementation validation measurement transmural left ventricle.