Brain Metastasis from Follicular Thyroid Carcinoma: Treatment with Sorafenib

摘要: Background: Sorafenib has shown promise in the treatment of patients with advanced or metastatic thyroid carcinoma. However, its therapeutic effect not been assessed brain metastases from follicular carcinoma (FTC). Here, we report a patient whom this was employed relatively favorable response. Patient and Methods: A 56-year-old woman had thyroidectomy 8 years previously for FTC. She subsequently developed lung metastases, which she received seven courses radioiodine (131I) therapy. right hemiplegia other symptoms found to have ∼5-cm lesion left parietal lobe. Radiosurgery total dose 28 Gy (7 Gy/day, 4 days) treat her ineffective, referred us. We treated sorafenib, 200 mg orally, on twice-daily basis. The intervention clinically radiographically using Response Evaluation Criteria Solid Tumors (RECIST). Summary...