Identification of 4-methyl-5-oxo-octane-1,8-dioic acid and the derivatives as metabolites of steroidal C,D-ring degradation in Comamonas testosteroni TA441.
作者： Masae Horinouchi , Michal Malon , Hiroshi Hirota , Toshiaki Hayashi
DOI: 10.1016/J.JSBMB.2018.07.008
关键词:
摘要: Comamonas testosteroni TA441 degrades steroids via 9, 17-dioxo-1, 2, 3, 4, 10, 19-hexanorandrostan-5-oic acid, which is presumed to be further degraded by β-oxidation. In …
sci-hub.se 参考文章(39)
Mikio Shikita, Paul Talalay, Inhibition of deoxyribonucleic acid-directed ribonucleic acid polymerase by extracts of steroid-induced and noninduced Pseudomonas testosteroni. Journal of Biological Chemistry. ,vol. 242, pp. 5650- 5659 ,(1967) , 10.1016/S0021-9258(18)99406-8
Y Nagata, T Nariya, R Ohtomo, M Fukuda, K Yano, M Takagi, Cloning and sequencing of a dehalogenase gene encoding an enzyme with hydrolase activity involved in the degradation of gamma-hexachlorocyclohexane in Pseudomonas paucimobilis. Journal of Bacteriology. ,vol. 175, pp. 6403- 6410 ,(1993) , 10.1128/JB.175.20.6403-6410.1993
A W Coulter, P Talalay, Studies on the Microbiological Degradation of Steroid Ring A Journal of Biological Chemistry. ,vol. 243, pp. 3238- 3247 ,(1968) , 10.1016/S0021-9258(18)93299-0
Charles J. Sih, S.S. Lee, Y.Y. Tsong, K.C. Wang, Mechanisms of Steroid Oxidation by Microorganisms Journal of Biological Chemistry. ,vol. 241, pp. 540- 550 ,(1966) , 10.1016/S0021-9258(18)96871-7
D.T. Gibson, K.C. Wang, Charles J. Sih, H. Whitlock, Mechanisms of Steroid Oxidation by Microorganisms Journal of Biological Chemistry. ,vol. 241, pp. 551- 559 ,(1966) , 10.1016/S0021-9258(18)96872-9
Masae Horinouchi, Toshiaki Hayashi, Hiroyuki Koshino, Michal Malon, Hiroshi Hirota, Toshiaki Kudo, Identification of 9α-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid and β-oxidation products of the C-17 side chain in cholic acid degradation by Comamonas testosteroni TA441. The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 143, pp. 306- 322 ,(2014) , 10.1016/J.JSBMB.2014.04.014
José Luis Pruneda-Paz, Mauricio Linares, Julio E Cabrera, Susana Genti-Raimondi, Identification of a novel steroid inducible gene associated with the βhsd locus of Comamonas testosteroni The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 88, pp. 91- 100 ,(2004) , 10.1016/J.JSBMB.2003.10.010
Jordi Benach, Charlotta Filling, Udo C. T. Oppermann, Pietro Roversi, Gérard Bricogne, Kurt D. Berndt, Hans Jörnvall, Rudolf Ladenstein, Structure of Bacterial 3beta/17beta-Hydroxysteroid Dehydrogenase at 1.2 A Resolution: A Model for Multiple Steroid Recognition Biochemistry. ,vol. 41, pp. 14659- 14668 ,(2002) , 10.1021/BI0203684
Clemens Grimm, Edmund Maser, Eric Möbus, Gerhard Klebe, Klaus Reuter, Ralf Ficner, The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family. Journal of Biological Chemistry. ,vol. 275, pp. 41333- 41339 ,(2000) , 10.1074/JBC.M007559200
Masae Horinouchi, Tomokazu Kurita, Toshiaki Hayashi, Toshiaki Kudo, Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Δ4(5)-isomerase and 3α- and 3β-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot. The Journal of Steroid Biochemistry and Molecular Biology. ,vol. 122, pp. 253- 263 ,(2010) , 10.1016/J.JSBMB.2010.06.002