Can a Charged Surfactant Unfold an Uncharged Protein?
作者： Casper Højgaard , Henrik Vinther Sørensen , Jan Skov Pedersen , Jakob Rahr Winther , Daniel Erik Otzen
DOI: 10.1016/J.BPJ.2018.10.022
关键词:
摘要: Abstract Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in manner similar to proteins, revealing formal charges are not required for SDS-induced unfolding or binding.
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