Comparable rates of lymph node metastasis and survival between diffuse type and intestinal type early gastric cancer patients: a large population-based study.

摘要: Background and Aims Limited evidence contradictory results exist regarding the impact of Lauren type, namely diffuse intestinal types, lymph node metastasis (LNM) prognosis for early gastric cancer (EGC). We aimed to compare LNM between type EGCs using comprehensive statistical analysis. Methods The Surveillance, Epidemiology, End Results (SEER) database was used identify all patients with surgically resected, histologically diagnosed, or EGC. Multivariate logistic regression, multivariate Cox competing risk model, propensity score matching were analyze association prognosis. identified 5593 from SEER database, including 4376 types 1217 types. No positive found (odds ratio, .93; 95% confidence interval [CI], .70-1.24; P = .62) after adjustment other factors. Moreover, diffuse-type showed a similar in both regression (HR [hazard ratio], .95; CI, .77-1.18; .66) model (subdistribution HR [SHR], .99; .80-1.22; .926). Propensity used, 733 matched did not find any .98; .71-1.37; .934) univariate (HR, .76-1.26; .893) (SHR, .893). Conclusions Diffuse-type EGC may have comparable intestinal-type Nevertheless, these should be carefully interpreted caution when choosing endoscopic resection instead surgery, because treatment choice depends on lymphovascular invasion rather than rate